In 2025, Montefiore Einstein’s Division of Cerebrovascular Neurosurgery continued to advance cerebrovascular science and expand access to next-generation treatment options for patients with complex neurovascular disorders. The Division published more than 100 peer-reviewed manuscripts, with several studies offering important insights that help guide current and future clinical practice.

These publications included a cost-effectiveness analysis of magnetic resonance angiography (MRA) screening for unruptured cerebral aneurysms in high-risk Black and Hispanic women and a Level 1 randomized controlled trial comparing open surgical clipping with endovascular treatment for ruptured intracranial aneurysms excluded from previous trials. Another notable publication presented a technical case series demonstrating a safe transophthalmic artery embolization approach for anterior skull base meningiomas, representing an important advancement in the management of complex skull base tumors. Together, these studies underscore Montefiore Einstein’s commitment to improving prevention, diagnosis and multidisciplinary management across the spectrum of cerebrovascular disease.

Montefiore Einstein was also selected as a site for the CHESS trial, the only National Institutes of Health-sponsored study evaluating the safety and efficacy of middle meningeal artery embolization with particles for the treatment of chronic subdural hematomas. It is the first randomized controlled trial to directly compare open surgical evacuation with endovascular embolization. David J. Altschul, MD, Surgical Director, Comprehensive Stroke Center, and Chief, Cerebrovascular Neurosurgery, serves as the site PI for this trial.

Montefiore Einstein was also selected by the American Heart Association/American Stroke Association in 2025 for a two-year educational grant supporting the Intracerebral Hemorrhage (ICH) Surgical Quality Improvement Initiative, recognizing Montefiore Einstein as a national leader in the care of patients with ICH. As one of only 15 participating sites in the nation, Montefiore Einstein is contributing to a collaborative project focused on testing new data and workflows to identify barriers and effective treatment models, including minimally invasive parafascicular surgery (MIPS), for the management of ICH. The findings will help inform national quality-improvement recommendations aimed at optimizing surgical interventions and improving outcomes for patients with hemorrhagic stroke.

Through the combination of high-impact publications, clinical trial leadership and national and international collaboration, the Montefiore Einstein Cerebrovascular Neurosurgery Division continues to push the field forward and expand what is possible in the care of patients with cerebrovascular disease. Montefiore Einstein’s commitment to excellence in research, innovation and patient-centered care is shaping the future of cerebrovascular treatment and improving outcomes.

We’re ranked in the top 1% of all hospitals in the nation for neurology and neurosurgery, according to U.S. News & World Report, and we are an international referral site for the most complex cases.

If you are interested in enrolling a patient in one of our clinical trials, please call 1-800-MD-MONTE.

Selected Publications & Trial Information

Peer-Reviewed Publications:

Park JJ, Reynolds J, Srivastava Y, Schechter C, et al. Cost-effectiveness analysis of MRA screening for cerebral aneurysms in Black and Hispanic women: A high risk population. Interventional Neuroradiology. Published online August 1, 2025. doi:10.1177/15910199251350215

Darsaut TE, Lecaros N, Comby PO, et al. A randomized trial comparing endovascular and surgical management of ruptured intracranial aneurysms excluded from previous trials. Journal of Neurosurgery. 2025;142(6):1794–1802. Published January 17, 2025. doi:10.3171/2024.8.JNS241276

Essibayi MA, Baker A, Ryvlin J, et al. Transophthalmic artery embolization of anterior skull base meningiomas: Technical case series. AJNR American Journal of Neuroradiology. 2025;46(6):1159–1165. Published June 3, 2025. doi:10.3174/ajnr.A8624

Clinical Trials:

SEAL™IT: Saccular Endovascular Aneurysm Lattice System Interventional Pivotal Trial (SEAL™IT)

ClinicalTrials.gov identifier: NCT05831202

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study (CHESS)

ClinicalTrials.gov identifier: NCT06347796